What is the most likely diagnosis?
- 32 year-old with fever and night sweats

Frontal and Lateral Chest Radiographs
- Achalasia
- Hodgkin Disease
- Metastatic Choriocarcinoma
- Histoplasmosis
- Sarcoid
Additional Image - Axial contrast-enhanced CT of the chest

Additional Images

Axial Contrast-enhanced CT of the Chest

Answer:
2. Hodgkin Disease
More (Click Discussion Tab)
Hodgkin Disease
General Considerations
- Half of patients with Hodgkin have mediastinal lymph node enlargement visible on chest x-ray.
- About 5-10% of patients may have mediastinal adenopathy without any other nodes involved
- Clinically, over 90% of patients with Hodgkin have enlarged nodes, the disease behaving most benignly when restricted to the neck
- Most have nodular sclerosing type