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LearningRadiology Imaging Signs
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Case of the Week 379




What sign is depicted on this image?

  • 58 year-old with abdominal pain and diarrhea



Axial CT view of abdomen with oral contrast

1. String sign
2. Egg-on-a-string sign
3. Accordion Sign
4. Mercedes Benz sign
5. Colon cut-off sign

Additional Images - None

 

Additional Images

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Answer:

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3. Accordion sign

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More (Click Discussion Tab)


Accordion Sign

General Considerations

  • The sign was originally described as alternating edematous haustral folds separated by mucosal ridges filled with oral contrast material
  • Simulated appearance of an accordion
  • It was first thought to be specific for severe Clostridium difficile–related colitis (pseudomembranous colitis)
    • Almost all cases of pseudomembranous colitis are associated with recent antibiotic therapy
  • C. difficile is the largest single cause of this sign

    More ...


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