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Case of the Week 351

What's the most likely diagnosis?

  • 36 year-old female with flank pain

Left Kidney-Contrast-Enhanced CT Urogram

  1. Hydronephrosis
  2. Renal Cell Carcinoma
  3. Xanthogranulomatous Pyelonephritis
  4. Cystic Nephroma
  5. Staghorn calculus

Additional Image - Axial contrast-enhanced CT of the upper abdomen


Additional Image



Axial contrast-enhanced CT of the upper abdomen




4. Cystic Nephroma



More (Click Discussion Tab)

Cystic Nephroma

General Considerations

  • Rare, unilateral multi-loculated cystic tumor lacking blastemal elements
  • Solitary, well-circumscribed
  • Non-communicating fluid-filled locules, surrounded by thick, fibrous capsule
  • Do not connect to the collecting system
  • Usually quite large (mean 7.6 cm by 9.7 cm)
  • Most common in lower pole
  • Bimodal occurrence
    • Affects males more often in childhood ( 3 months-4 years)
      • 50% cystic nephromas and 50% CPDN (see below)
    • Females more frequently in adulthood (>30)

    More ...


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