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Case of the Week 545



What is the most likely diagnosis?

  • 51 year-old female with wrist pain



Frontal view of right wrist

  1. Hemophilia
  2. Psoriasis
  3. Neurofibromatosis
  4. Rheumatoid Arthritis
  5. Hyperparathyroidism

No additional images

 

Additional Images

 


None


Answer:

 

4. Rheumatoid Arthritis

 

More (Click Discussion Tab)

 

 

Rheumatoid Arthritis

General Considerations

  • Cause ─ unknown
    • Possible genetic predisposition
    • Questionable reaction to antigen from Epstein-Barr virus
  • Age-Highest incidence 40-50 years
    • Female preponderance 3:1 under the age of 40; equal distribution over 40 years
  • Pathogenesis
    • Injury to synovial endothelial cells leads to
    • Synovitis with synovial hypertrophy which leads to
    • Impaired nutrition with necrosis of cartilage and resultant
    • Joint narrowing
      • Subluxation
      • Ankylosis

MORE . . .

 


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LearningRadiology.com
is an award-winning educational website aimed primarily at medical students and radiology residents-in-training, containing  lectures, handouts, images, Cases of the Week, archives of cases, quizzes, flashcards of differential diagnoses and “most commons” lists, primarily in the areas of chest, GI, GU cardiac, bone and neuroradiology.