What is the most likely diagnosis?
- 38 year-old with blood dyscrasia
Frontal Chest Radiograph
- Multiple myeloma
- Idiopathic thrombocytopenia
- Thalassemia
- Pernicious anemia
- Neurofibromatosis
Additional Images - Lateral Chest Radiograph
Additional Images
Lateral Chest Radiograph
Answer:
3. Thalassemia
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Extramedullary hematopoiesis in Thalassemia
General Considerations
- Response to insufficient blood cell production by production of blood elements outside of the marrow cavity
- Most often due to hemolytic anemias such as sickle cell anemia, thalassemia and hereditary spherocytosis
- May also be seen in prolonged iron deficiency anemia, myelofibrosis and sclerosis, polycythemia, leukemia and lymphoma