Learning Radiology xray montage

Glioblastoma Multiforme

Gliomas of the brain

    • Most common primary supratentorial, intraaxial mass in adult

    • Gliomas account for 35-45% of all intracranial tumors and glioblastoma multiforme accounts for more than half of them, astrocytomas about 20% and the remainder split between ependymomas, medulloblastoma, oligodendroglioma

    • Glioblastoma multiforme has the worst prognosis of all gliomas

    • Occurs more commonly in males between 65-75 years of age, especially in the frontal and temporal lobes

    • Recognizing glioblastoma multiforme

      • As the most aggressive of tumors, glioblastoma multiforme frequently demonstrates necrosis within the tumor

      • The tumor infiltrates the surrounding brain tissue, frequently crossing the white matter tracts of the corpus callosum to the opposite cerebral hemisphere producing a pattern called a butterfly glioma

      • It tends to produce considerable vasogenic edema and mass effect and contrast enhances, at least in part


     Glioblastoma Multiforme

    Glioblastoma Multiforme. There is a large contrast-enhancing mass in the right frontal region (red arrow) with a large amount of surrounding vasogenic edema (white arrows) and shift of the falx to the left from mass effect (black arrow).