Learning Radiology xray montage
 
 
 
 
 

Non-Ossifying Fibroma
Nonosteogenic fibroma, fibroxanthoma, xanthogranuloma of bone



  • 30 to 40% children over two years have one or more lesions
  • Most common between 8-20 years of age
  • Usually occur in metaphysis of one (75%) or more (25%) of the tubular bones

Non-Ossifying FibromaNon-Ossifying Fibroma

  • Most often occur in lower extremities around knee
    • Fewer than 10% occur in upper extremities

  • Characteristics

    • Geographic
    • Lytic
    • Multilobulated
    • Metaphyseal
    • Usually intramedullary
    • Eccentric
    • Well-marginated
    • Sclerotic rim
    • Endosteal scalloping
  • Most lesions heal spontaneously by being replaced with normal bone
    • Migrate away from epiphysis
  • May undergo pathologic fracture or rarely cause rickets
    • Do not undergo malignant transformation