GI Imaging Differential Diagnoses

Multiple Esophageal Ulcers
Solitary Esophageal Ulcer
Distal Esophageal Stricture
Mid-esophageal stricture
Esophageal Mucosal Nodularity
Long esophageal stricture
Thickened esophageal folds
Solitary esophageal mass
Gastric ulcers, no mass
Target lesions in GI tract
Thickened Gastric Folds
Gastric Non-distensibility
Linitis Plastica
Gastric outlet obstruction
Gastric dilatation
Widening of retrogastric space
Antral Pad Sign
Diseases that cross the pylorus
Multiple Duodenal Filling Defects
Thickened Duodenal Folds
Duodenal-Biliary fistula
Duodenal Obstruction
Widening of duodenal sweep
Dilated small bowel, No fold thickening
Multiple small bowel masses
Separation of small bowel loops
Multiple Colonic Filling Defects
Smooth Colonic Stricture
Ileocecal disease
Coned Cecum
Cecal Filling defect
Double tracking of Colon
Colon Thumbprinting
Smooth Colon
Widened Presacral space
Rectal Narrowing
 

Multiple Esophageal Ulcers

  1. Reflux
  2. Infectious-HSV, Candida
  3. Drug induced
  4. Barrett’s BACK to TOP 

Solitary Esophageal Ulcer

  1. HIV
  2. CMV BACK to TOP

Distal Esophageal Stricture

  1. Peptic strictures
  2. Barrett’s
  3. Carcinoma-Gastric,esophageal
  4. Achalasia

Mid-esophageal stricture

  1. Barrett’s
  2. Radiation
  3. Ingestion of corrosives
  4. Metastases to mediastinum BACK to TOP

Esophageal Mucosal Nodularity

  1. Reflux
  2. Candida
  3. Glycogenic Acanthosis
  4. Barrett’s BACK to TOP 

Long esophageal stricture

  1. Lye
  2. NG Tube  (prolonged use)
  3. Radiation BACK to TOP

Thickened esophageal folds

  1. Varices
  2. Varicoid carcinoma
  3. Reflux esophagitis
  4. Lymphoma BACK to TOP

Solitary esophageal mass

  1. Leiomyoma
  2. Fibrovascular polyp
  3. Inflammatory esophagogastric polyp
  4. Papilloma
  5. Carcinoma BACK to TOP

Gastric ulcers, no mass

  1. H. Pylori
  2. Aspirin
  3. Crohn’s
  4. Zollinger-Ellison syndrome BACK to TOP

Target lesions in GI tract

  1. Hematogenous metastases-Breast, lung
  2. Kaposi’s Sarcoma
  3. Melanoma BACK to TOP 

Thickened Gastric Folds

  1. Gastritis-Hypertrophic, H. Pylori
  2. Menetrier’s disease
  3. Zollinger Ellison syndrome
  4. Varices
  5. Lymphoma BACK to TOP 

Gastric Non-distensibility

  1. Carcinoma-Primary, metastatic
  2. Lymphoma
  3. Atrophic gastritis
  4. Scarring from PUD
  5. Linitis Plastica of the Stomach BACK to TOP

Linitis Plastica

  1. Pancreatic tumor
  2. Lymphoma
  3. Amyloid
  4. Sarcoid/Syphilis
  5. TB
  6. Ingested Corrosives
  7. CA of stomach BACK to TOP 

Gastric outlet obstruction

  1. Peptic ulcer disease-Acute or chronic
  2. Carcinoma-Primary, Metastatic (pancreatic)
  3. Gastric volvulus
  4. Antral diaphragm/web
  5. Pyloric stenosis in children BACK to TOP 

Gastric dilatation

  1. Diabetes
  2. Electrolyte/acid-base imbalance
  3. Neuromuscular disorder
  4. Abdominal surgery
  5. Abdominal trauma BACK to TOP 

Widening of retrogastric space

  1. Pancreatic mass
  2. Retroperitoneal mass
  3. Exophytic posterior wall gastric tumor
  4. Aortic aneurysm BACK to TOP 

Antral Pad Sign

  1. Pancreatic cancer
  2. Pancreatic pseudocyst
  3. Gallbladder (normal or distended) BACK to TOP 

Diseases that cross the pylorus

  1. Lymphoma
  2. Carcinoma
  3. Crohn’s Disease
  4. Peptic ulcer disease
  5. TB
  6. Eosinophilic Gastroenteritis BACK to TOP 

Multiple Duodenal Filling Defects

  1. Brunner’s gland hyperplasia
  2. Polyps
  3. Adenomatous, hyperplastic
  4. Lymphoma BACK to TOP 

Thickened Duodenal Folds

  1. Duodenitis
  2. Chronic Renal Failure
  3. Pancreatitis
  4. Zollinger-Ellison Syndrome
  5. Varices
  6. Lymphoma BACK to TOP 

Duodenal-Biliary fistula

  1. Prior sphincterotomy
  2. Cholecystitis
  3. Gallbladder carcinoma
  4. Duodenal carcinoma BACK to TOP 

Duodenal Obstruction

  1. Congenital duodenal atresia/stenosis
  2. Annular pancreas
  3. Midgut volvulus
  4. Carcinoma
  5. SMA syndrome
  6. Intramural hematoma BACK to TOP

Widening of duodenal sweep

  1. Pancreatic Disease-Pancreatitis, pseudocyst, tumor
  2. Lymphadenopathy
  3. Aortic Aneurysm
  4. Choledochal cyst BACK to TOP 

Dilated small bowel, No fold thickening

  1. Scleroderma
  2. Sprue
  3. Small Bowel Obstruction BACK to TOP 

Multiple small bowel masses

  1. Polyposis (Peutz-Jeghers)
  2. Lymphoma
  3. Metastases BACK to TOP 

Separation of small bowel loops

  1. Thickening of bowel wall
  2. Carcinoid
  3. Crohn’s Disease
  4. Ascites
  5. Peritoneal metastases
  6. Retractile mesenteritis BACK to TOP 

Multiple Colonic Filling Defects 

  1. Polyps (polyposis)
  2. Pseudopolyps (UC)
  3. Lymphoma
  4. Cystic Pneumatosis  BACK to TOP

Smooth Colonic Stricture

  1. Ulcerative Colitis
  2. Crohn’s Disease
  3. Radiation
  4. Ischemia  BACK to TOP

Ileocecal disease

  1. Crohn’s Disease
  2. Lymphoma
  3. TB
  4. Cancer (colon adenocarcinoma, carcinoid) BACK to TOP

Coned Cecum

  1. Amebiasis
  2. Crohn’s Disease
  3. TB BACK to TOP 

Cecal Filling defect

  1. Appendicitis/Mucocele
  2. Crohn’s Disease
  3. Cecal neoplasm
  4. Ileocolic intussusception
  5. Lymphoma BACK to TOP 

Double tracking of Colon

  1. Crohn’s Disease
  2. Diverticulitis
  3. Adenocarcinoma BACK to TOP

Colon Thumbprinting

  1. Ulcerative Colitis
  2. Ischemia
  3. Hemorrhage
  4. Lymphoma BACK to TOP

Smooth Colon

  1. Ulcerative colitis
  2. Cathartic Colon
  3. Post ischemic
  4. Post radiation  BACK to TOP

Widened Presacral space

  1. Ulcerative colitis
  2. Pelvic lipomatosis
  3. Crohn’s Disease
  4. Rectal tumor
  5. Sacral tumor  BACK to TOP

Rectal Narrowing

  1. Ulcerative Colitis
  2. Pelvic Lipomatosis
  3. Lymphogranuloma Venereum (LGV)
  4. Solitary Rectal Ulcer Syndrome
  5. Radiation BACK to TOP
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