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Chest Imaging Differential Diagnoses

 
Acute Airspace Disease
1.   Pulmonary  edema
2.   Pneumonia
3.   Aspiration
4.   Hemorrhage   BACK to TOP
Anterior  Mediastinal Masses
1.   Thymoma
2.   Teratoma
3.   Substernal thyroid
4.   Lymphoma   BACK to TOP
Opacified Hemithorax
1.   Atelectasis
2.   Effusion
3.   Pneumonia
4.   Post-pneumonectomy   BACK to TOP
Chronic Airspace Disease
1.   Alveolar  cell ca         
2.   Alveolar  sarcoid       
3.   Lymphoma    
4.   Alveolar  proteinosis   BACK to TOP
Large Cavitary Lung Lesions
1.   Abscess
2.   Carcinoma
3.   TB  BACK to TOP
Bibasilar Interstitial Disease
1.   Bronchiectasis
2.   Aspiration
3.   DIP
4.   Asbestosis
5.   Sarcoidosis
6.   Scleroderma    BACK to TOP
Micronodular Lung Disease
1.   Mets
2.   Sarcoid
3.   Pneumoconiosis
4.   Miliary TB   BACK to TOP  
Pulmonary Fibrosis
1.   Pneumoconiosis
2.   Interstitial  Pneumonia
3.   Granulomatous  disease
4.   Neoplastic  disease
5.   Idiopathic  fibrosis
6.   Collagen  vascular disease  BACK to TOP
Small Cavitary Lung Lesions
1.   Septic  emboli
2.   Rheumatoid  nodules
3.   Squamous or  transitional cell mets
4.   Wegener’s  Granulomatosis   BACK to TOP
Lymphangitic Spread to the Lungs
1.   Lung ca
2.   Breast ca
3.   Stomach ca
4.   Pancreas ca
5.   Laryngeal  ca
6.   Cervical ca    BACK to TOP
Multiple Lung Nodules
1.   Mets
2.   Wegener’s  granulomatosis
3.   Rheumatoid  nodules
4.   AVMs
5.   Septic  emboli   BACK to TOP
Shifting Infiltrates
1.   Loeffler’s syndrome
2.   ABPA
3.   Asthma
4.   Polyarteritis
5.   Viral pneumonia   BACK to TOP
Unilateral Hyperlucent Lung
1.   Swyer James  syndrome
2.   Pulmonary  embolism
3.   Pneumothorax
4.   Obstructive  emphysema   BACK to TOP
Rapidly Clearing Airspace Disease
1.   Pneumococcal  pneumonia
2.   Hemorrhage
3.   Pulmonary  edema
4.   Aspiration   BACK to TOP
Cavitating Pneumonia
1.   Staph
2.   Strep
3.   TB
4.   Gram  negative (klebsiella)   BACK to TOP
Middle Mediastinal Masses
1.   Lymphadenopathy
2.   Aneurysms
3.   Esophageal  duplication
4.   Bronchogenic  cysts  BACK to TOP
Masses with Air Bronchograms
1.   Lymphoma
2.   Alveolar cell ca
3.   Pseudolymphoma (Maltoma)  BACK to TOP
Cavities Containing Masses
1.   Aspergillosis
2.   Cavitating  bronchogenic ca
3.   Hydatid  cyst
4.   Tuberculosis  BACK to TOP
Infiltrates with Effusion
1.   Staph  pneumonia
2.   Strep  pneumonia
3.   TB
4.   Pulmonary  infarct
“Mass”+ ipsilateral adenopathy
1.   Bronchogenic  ca
2.   Lymphoma
3.   TB  BACK to TOP
Solitary Pulmonary Nodule
1.   Bronchogenic  ca
2.   Hamartoma
3.   Histoplasmoma
4.   TB  granuloma
5.   Bronchial  adenoma
6.   Solitary  met
7.   Round  pneumonia
8.   Rounded  atelectasis     BACK to TOP
Pleural Effusion
1.   CHF
2.   Mets
3.   Pancreatitis
4.   Pulmonary  embolism
5.   Trauma
6.   Empyema
7.   Collagen vascular
8.   Ovarian tumor (Meig’s Syndrome)
9.   Chylothorax    BACK to TOP
Multiple Small Calcifications
1.   Histoplasmosis
2.   Silicosis
3.   Chicken pox  pneumonia
4.   Pulmonary  ossification 2° MS
5.   Alveolar microlithiasis      BACK to TOP
Posterior  Mediastinal Masses
1.   Neurogenic tumors
2.   Lymphadenopathy
3.   Extramedullary  hematopoiesis   BACK to TOP
Mediastinal Adenopathy
1.   Bronchogenic  ca
2.   Lymphoma
3.   TB
4.   Mets
5.   Sarcoid    BACK to TOP
Lung Disease & Rib Destruction
1.   Bronchogenic  ca, i.e. Pancoast tumor
2.   Actinomycosis
3.   Blastomycosis
4.   Multiple  myeloma    BACK to TOP             
Pleural Calcification
1.   Old TB  empyema
2.   Asbestos  exposure
3.   Hemothorax     BACK to TOP
“Masses” in Cardiophrenic Angle
1.   Sequestration
2.   Diaphragmatic  hernia
3.   Pericardial  cyst   BACK to TOP
Unilateral Pulmonary Edema
1.   Aspiration
2.   Disease in  other lung, e.g. COPD
3.   Postural
4.   Rapid  expansion of PTX   BACK to TOP
Reverse Pulmonary Edema
1.   Eosinophilic  lung disease, e.g. Loeffler’s
2.   Sarcoid
3.   Pulmonary  contusions    BACK to TOP
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