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Case of the Week 304



What's the most likely diagnosis?

  • 63 year old with diarrhea

  1. Shock bowel
  2. Ovarian carcinoma
  3. C. difficile colitis
  4. Small bowel obstruction
  5. Crohn disease

Additional Image-CT of the pelvis

 

Additional Image

 

CT of the Pelvis


Answer:

 


3. C. difficile colitis (Pseudomembranous colitis)

 

 

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C. difficile colitis

General Considerations

  • Characterized by pseudomembrane, a yellowish-white plaque seen on  the mucosa
  • Usually involves colon, although small bowel can be involved
  • Occurs primarily in hospitalized patients
    • Almost 20% of hospitalized patients acquire C difficile during hospitalization
  • Occurs in adults, especially the elderly, more often than children
  • Almost always secondary to antibiotic therapy with overgrowth of Clostridium difficile, a gram-positive, anaerobic bacillus normally present in about 2-3 % of healthy adults

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