Image DDX




Case of the Week 291

What's the most likely diagnosis?

  • 2 year-old male with stridor

  1. Enlarged adenoids
  2. Enlarged tonsils
  3. Papilloma
  4. Croup
  5. Epiglottitis

No additional images


Additional Image

No additional images



3. Laryngeal Papilloma



More (Click Discussion Tab)

Laryngeal Papillioma

General Considerations


  • Most common benign tumor of the trachea in children (60% of all benign tumors)
  • 2nd most common benign tumor of trachea in adults
    • Majority of primary tracheal tumors are malignant
  • In over 80% of cases, multiple papillomas occur in the trachea
  • Tracheal papilloma is associated with a laryngeal papilloma in 36%
  • Because of its high recurrence rate, it is also called Recurrent Respiratory Papillomatosis (RRP)
  • Caused by the human papilloma virus (HPV)
    • Most often types 6 and 11
    • Also the cause of skin warts and genital warts
    • Transmission of recurrent respiratory papillomatosis is believed to occur, at least in part, from mother’s infected cervix during childbirth
    • HPV is responsible for most cervical cancers and about 25% of head and neck cancers
  • Most common in children and then again 20-40 years of age
  • Significant recurrence rate may lead to numerous operative removals
  • Not the same as vocal cord polyps or nodules

More ...

10 Most Viewed is an award-winning educational site aimed primarily at medical students and radiology residents-in-training, containing  lectures, handouts, images, Cases of the Week, archives of case quizzes, flashcards of differential diagnoses and “most commons” lists, primarily in the areas of chest, GI, cardiac, and bone radiology.