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Non-Ossifying Fibroma
Nonosteogenic fibroma,
fibroxanthoma, xanthogranuloma of bone
- 30 to 40% children
over two years have one or more lesions
- Most common
between 8-20 years of age
- Usually occur in
metaphysis of one (75%) or more (25%) of the tubular bones
- Most often occur
in lower extremities around knee
- Fewer than 10%
occur in upper extremities
- Characteristics
- Geographic
- Lytic
- Multilobulated
- Metaphyseal
- Usually
intramedullary
- Eccentric
- Well-marginated
- Sclerotic rim
- Endosteal
scalloping
- Most lesions heal
spontaneously by being replaced with normal bone
- Migrate away
from epiphysis
- May undergo
pathologic fracture or rarely cause rickets
- Do not undergo
malignant transformation
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