Hamartoma of Lung

• Hamartoma is composed of tissues normally found at this location but in abnormal quantity, mixture or arrangement

INCIDENCE

               • 0.25% in population

               • 8% of all solitary pulmonary nodules

               • Most common benign lung tumor

               • 5th and 6th decade peak  

               • Male to female ratio of 3:1

CLINICAL

               • Mostly asymptomatic

               • Cough

               • Fever (with postobstructive pneumonia)

               • Hemoptysis (rare)

LOCATION

               • 2/3 are peripheral

               • Endobronchial in 10%

               • Rarely multiple

X-ray

               • Round, smooth mass_—increase in size slowly

               • Calcification in 15% — pathognomonic if popcorn type

               • Fat in 50% —detected by CT

               • Cavitation extremely rare

DDX

               • Other causes of a solitary pulmonary nodule

                              • Bronchial adenoma

                              • Bronchogenic ca

                              • Granuloma

                              • Lipoid pneumonia (both contain fat)

Hamartoma of the right lung seen on axial CT (upper) and close-up (lower)
contains both calcification and fat, characteristic of a hamartoma

Hamartoma of the left lower lobe. On the lateral chest radiograph, there is a nodule seen at the lung base (white arrows) that appears quite dense suggesting calcification. The close-up view of the CT scan of the left lower lobe demonstrates the typical "popcorn" calcification of a hamartoma (red arrow).